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<p>Hallo, leider ist da nichts abrufbar. nur ein Referenzhandbuch
und ein Lizenztext und die Versio 4.2.0</p>
<p>vg matthias nagel</p>
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<div class="moz-cite-prefix">Am 24.12.2022 um 15:18 schrieb Johannes
W. Dietrich via SPINA:<br>
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cite="mid:647EBE63-BB34-480C-9A0A-369B2006BF8F@ruhr-uni-bochum.de">
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As a kind of Christmas gift we released a major new version of the
SPINA Functions for the statistical programming language S
(including the environment R).
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<div class="">This new version implements SPINA Carb for the
evaluation of insulin-glucose homeostasis (while providing the
established markers of thyroid homeostasis as well) and is
capable of calculating the secretory capacity of pancreatic beta
cells (SPINA-GBeta) and insulin receptor gain (SPINA-GR). This
version facilitates the statistical evaluation of carbohydrate
metabolism with S scripts. The algorithms for the calculation
are derived and explained in [1]</div>
<div class=""><br class="">
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<div class="">Version 5.0 of the SPINA Functions is available
from <a href="https://sourceforge.net/projects/spina/files/SPINA
for domain-specific applications/S scripts/"
class="moz-txt-link-freetext" moz-do-not-send="true">https://sourceforge.net/projects/spina/files/SPINA%20for%20domain-specific%20applications/S%20scripts/</a> or
via zenodo from <a
href="https://zenodo.org/record/7479857#.Y6cI9S1XacY"
class="moz-txt-link-freetext" moz-do-not-send="true">https://zenodo.org/record/7479857#.Y6cI9S1XacY</a> .</div>
<div class=""><br class="">
</div>
<div class="">Merry Christmas and Happy Holidays,</div>
<div class="">JWD</div>
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</div>
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<div class="">Reference:</div>
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</div>
<div class="">1. Dietrich JW, Dasgupta R, Anoop S, Jebasingh F,
Kurian ME, Inbakumari M, Boehm BO, Thomas N. SPINA Carb: a
simple mathematical model supporting fast in-vivo estimation of
insulin sensitivity and beta cell function. Sci Rep. 2022 Oct
21;12(1):17659. doi: 10.1038/s41598-022-22531-3. PMID: 36271244;
PMCID: PMC9587026. <a
href="https://pubmed.ncbi.nlm.nih.gov/36271244/"
class="moz-txt-link-freetext" moz-do-not-send="true">https://pubmed.ncbi.nlm.nih.gov/36271244/</a> <br
class="">
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<div style="font-family: Helvetica; font-size: 12px;
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start; text-indent: 0px; text-transform: none;
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-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --
-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --</div>
<div style="caret-color: rgb(0, 0, 0); color: rgb(0, 0,
0); letter-spacing: normal; text-transform: none;
white-space: normal; word-spacing: 0px; text-decoration:
none; -webkit-text-stroke-width: 0px; font-family:
Helvetica; font-size: 12px; font-style: normal;
font-variant-caps: normal; font-weight: normal;
text-align: start; text-indent: 0px;">-- PD Dr. med.
Johannes W. Dietrich<br class="">
-- Diabetes, Endocrinology and Metabolism Section<br
class="">
-- Department of Medicine I, St. Josef Hospital<br
class="">
-- Ruhr University of Bochum<br class="">
-- Gudrunstr. 56, D-44791 Bochum, NRW, Germany<br
class="">
-- Phone: +49:234:509-2311, Fax: +49:234:509-2309<br
class="">
-- eMail: "<a
href="mailto:johannes.dietrich@ruhr-uni-bochum.de"
class="moz-txt-link-freetext" moz-do-not-send="true">johannes.dietrich@ruhr-uni-bochum.de</a>“</div>
<div style="caret-color: rgb(0, 0, 0); color: rgb(0, 0,
0); letter-spacing: normal; text-transform: none;
white-space: normal; word-spacing: 0px; text-decoration:
none; -webkit-text-stroke-width: 0px; font-family:
Helvetica; font-size: 12px; font-style: normal;
font-variant-caps: normal; font-weight: normal;
text-align: start; text-indent: 0px;">--
ORCID 0000-0002-1185-3549</div>
<div style="caret-color: rgb(0, 0, 0); color: rgb(0, 0,
0); letter-spacing: normal; text-transform: none;
white-space: normal; word-spacing: 0px; text-decoration:
none; -webkit-text-stroke-width: 0px; font-family:
Helvetica; font-size: 12px; font-style: normal;
font-variant-caps: normal; font-weight: normal;
text-align: start; text-indent: 0px;">-- <a
href="http://www.thyreologie.com.de"
class="moz-txt-link-freetext" moz-do-not-send="true">http://www.thyreologie.com.de</a><br
class="">
-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --
-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- —<br
class="">
<br class="">
Announcement: Our eBook "Thyroid Hormones and
Cardiac Arrhythmia“ has been published. </div>
<div style="caret-color: rgb(0, 0, 0); color: rgb(0, 0,
0); letter-spacing: normal; text-transform: none;
white-space: normal; word-spacing: 0px; text-decoration:
none; -webkit-text-stroke-width: 0px; font-family:
Helvetica; font-size: 12px; font-style: normal;
font-variant-caps: normal; font-weight: normal;
text-align: start; text-indent: 0px;">You may want
to visit <a
href="http://dx.doi.org/10.3389/978-2-83250-253-2"
class="moz-txt-link-freetext" moz-do-not-send="true">http://dx.doi.org/10.3389/978-2-83250-253-2</a>
or <a
href="https://www.frontiersin.org/research-topics/16898/thyroid-hormones-and-cardiac-arrhythmia"
class="moz-txt-link-freetext" moz-do-not-send="true">https://www.frontiersin.org/research-topics/16898/thyroid-hormones-and-cardiac-arrhythmia</a>.<br
class="">
<br class="">
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