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<p>ach so, sorry, davon vollständig also doch viel zu wenig, und hat
mir einfach vorgestellt, dass es schon die neue
Endanwender-Version gibt.</p>
<p>Also alles Gute, viel Erfolg für das Neue Jahr und Danke für die
Antwort!</p>
<p>mfg Ihr Matthias Nagel<br>
</p>
<div class="moz-cite-prefix">Am 04.01.2023 um 17:59 schrieb Johannes
W. Dietrich via SPINA:<br>
</div>
<blockquote type="cite"
cite="mid:D50B601B-D37A-4C74-93A6-8C99E7774CE8@ruhr-uni-bochum.de">
<meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
Lieber Herr Nagel,
<div class=""><br class="">
</div>
<div class="">Sie können Version 5.0 von <a
href="https://sourceforge.net/projects/spina/files/SPINA for
domain-specific applications/S scripts/"
class="moz-txt-link-freetext" moz-do-not-send="true">https://sourceforge.net/projects/spina/files/SPINA%20for%20domain-specific%20applications/S%20scripts/</a> laden.</div>
<div class=""><br class="">
</div>
<div class="">Der Link enthält nur Funktionen für die statistische
Programmiersprache S. Sie unterstützen die Parameter von SPINA
Thyr (SPINA-GT und SPINA-GD sowie als Ergänzung TSH-Index nach
Jostel und TTSI) und seit Version 5.0 zusätzlich die Parameter
von SPINA Carb (SPINA-GBeta und SPINA-GR sowie ergänzend
HOMA-Beta, HOMA-IR und QUICKI).</div>
<div class=""><br class="">
</div>
<div class="">Eine GUI-Version folgt später. Die jetzige Version
ist für die Unterstützung wissenschaftlicher Berechnungen in
Studien gedacht.</div>
<div class=""><br class="">
</div>
<div class="">MfG,</div>
<div class="">JWD<br class="">
<div class="">
<div><br class="">
-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --
-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --<br class="">
-- PD Dr. med. Johannes W. Dietrich<br class="">
-- Diabetes, Endocrinology and Metabolism Section<br
class="">
-- Department of Medicine I, St. Josef Hospital<br class="">
-- Ruhr University of Bochum<br class="">
-- Gudrunstr. 56, D-44791 Bochum, NRW, Germany<br class="">
-- Phone: +49:234:509-2311, Fax: +49:234:509-2309<br
class="">
-- eMail: "<a
href="mailto:johannes.dietrich@ruhr-uni-bochum.de"
class="moz-txt-link-freetext" moz-do-not-send="true">johannes.dietrich@ruhr-uni-bochum.de</a>“<br
class="">
-- ORCID 0000-0002-1185-3549<br class="">
-- <a href="http://www.thyreologie.com.de"
class="moz-txt-link-freetext" moz-do-not-send="true">http://www.thyreologie.com.de</a><br
class="">
-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --
-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- —<br class="">
<br class="">
Announcement: Our eBook "Thyroid Hormones and Cardiac
Arrhythmia“ has been published. <br class="">
You may want to visit <a
href="http://dx.doi.org/10.3389/978-2-83250-253-2"
class="moz-txt-link-freetext" moz-do-not-send="true">http://dx.doi.org/10.3389/978-2-83250-253-2</a>
or <a
href="https://www.frontiersin.org/research-topics/16898/thyroid-hormones-and-cardiac-arrhythmia"
class="moz-txt-link-freetext" moz-do-not-send="true">https://www.frontiersin.org/research-topics/16898/thyroid-hormones-and-cardiac-arrhythmia</a>.<br
class="">
<br class="">
<br class="">
<br class="">
</div>
</div>
<div><br class="">
<blockquote type="cite" class="">
<div class="">Am 03.01.2023 um 12:04 schrieb M. Nagel <<a
href="mailto:nagel@nuklearmedizin-nagel.de"
class="moz-txt-link-freetext" moz-do-not-send="true">nagel@nuklearmedizin-nagel.de</a>>:</div>
<br class="Apple-interchange-newline">
<div class="">
<meta http-equiv="Content-Type" content="text/html;
charset=UTF-8" class="">
<div class="">
<p class="">Hallo, leider ist da nichts abrufbar. nur
ein Referenzhandbuch und ein Lizenztext und die Versio
4.2.0</p>
<p class="">vg matthias nagel</p>
<p class=""><br class="">
</p>
<p class=""><br class="">
</p>
<div class="moz-cite-prefix">Am 24.12.2022 um 15:18
schrieb Johannes W. Dietrich via SPINA:<br class="">
</div>
<blockquote type="cite"
cite="mid:647EBE63-BB34-480C-9A0A-369B2006BF8F@ruhr-uni-bochum.de"
class="">
<meta http-equiv="Content-Type" content="text/html;
charset=UTF-8" class="">
As a kind of Christmas gift we released a major new
version of the SPINA Functions for the statistical
programming language S (including the environment R).
<div class=""><br class="">
</div>
<div class="">This new version implements SPINA Carb
for the evaluation of insulin-glucose homeostasis
(while providing the established markers of thyroid
homeostasis as well) and is capable of calculating
the secretory capacity of pancreatic beta cells
(SPINA-GBeta) and insulin receptor gain (SPINA-GR).
This version facilitates the statistical evaluation
of carbohydrate metabolism with S scripts. The
algorithms for the calculation are derived and
explained in [1]</div>
<div class=""><br class="">
</div>
<div class="">Version 5.0 of the SPINA Functions is
available from <a
href="https://sourceforge.net/projects/spina/files/SPINA%20%20%20%20%20%20%20%20%20%20for%20domain-specific%20applications/S%20scripts/"
class="moz-txt-link-freetext"
moz-do-not-send="true">https://sourceforge.net/projects/spina/files/SPINA%20for%20domain-specific%20applications/S%20scripts/</a> or
via zenodo from <a
href="https://zenodo.org/record/7479857#.Y6cI9S1XacY"
class="moz-txt-link-freetext"
moz-do-not-send="true">https://zenodo.org/record/7479857#.Y6cI9S1XacY</a> .</div>
<div class=""><br class="">
</div>
<div class="">Merry Christmas and Happy Holidays,</div>
<div class="">JWD</div>
<div class=""><br class="">
</div>
<div class=""><br class="">
</div>
<div class="">Reference:</div>
<div class=""><br class="">
</div>
<div class="">1. Dietrich JW, Dasgupta R, Anoop S,
Jebasingh F, Kurian ME, Inbakumari M, Boehm BO,
Thomas N. SPINA Carb: a simple mathematical model
supporting fast in-vivo estimation of insulin
sensitivity and beta cell function. Sci Rep. 2022
Oct 21;12(1):17659. doi: 10.1038/s41598-022-22531-3.
PMID: 36271244; PMCID: PMC9587026. <a
href="https://pubmed.ncbi.nlm.nih.gov/36271244/"
class="moz-txt-link-freetext"
moz-do-not-send="true">https://pubmed.ncbi.nlm.nih.gov/36271244/</a> <br
class="">
<br class="">
<div class="">
<div dir="auto" style="text-align: start;
text-indent: 0px; word-wrap: break-word;
-webkit-nbsp-mode: space; line-break:
after-white-space;" class="">
<div dir="auto" style="text-align: start;
text-indent: 0px; word-wrap: break-word;
-webkit-nbsp-mode: space; line-break:
after-white-space;" class="">
<div style="font-family: Helvetica; font-size:
12px; font-style: normal; font-variant-caps:
normal; font-weight: normal; letter-spacing:
normal; text-align: start; text-indent: 0px;
text-transform: none; white-space: normal;
word-spacing: 0px;
-webkit-text-stroke-width: 0px;
text-decoration: none; caret-color: rgb(0,
0, 0);" class=""><br
class="Apple-interchange-newline">
-- -- -- -- -- -- -- -- -- -- -- -- -- -- --
-- -- -- -- -- -- -- -- -- -- -- -- -- -- --
-- -- -- -- -- --</div>
<div style="caret-color: rgb(0, 0, 0);
letter-spacing: normal; text-transform:
none; white-space: normal; word-spacing:
0px; text-decoration: none;
-webkit-text-stroke-width: 0px; font-family:
Helvetica; font-size: 12px; font-style:
normal; font-variant-caps: normal;
font-weight: normal; text-align: start;
text-indent: 0px;" class="">-- PD Dr. med.
Johannes W. Dietrich<br class="">
-- Diabetes, Endocrinology and Metabolism
Section<br class="">
-- Department of Medicine I, St. Josef
Hospital<br class="">
-- Ruhr University of Bochum<br class="">
-- Gudrunstr. 56, D-44791 Bochum, NRW,
Germany<br class="">
-- Phone: +49:234:509-2311, Fax:
+49:234:509-2309<br class="">
-- eMail: "<a
href="mailto:johannes.dietrich@ruhr-uni-bochum.de"
class="moz-txt-link-freetext"
moz-do-not-send="true">johannes.dietrich@ruhr-uni-bochum.de</a>“</div>
<div style="caret-color: rgb(0, 0, 0);
letter-spacing: normal; text-transform:
none; white-space: normal; word-spacing:
0px; text-decoration: none;
-webkit-text-stroke-width: 0px; font-family:
Helvetica; font-size: 12px; font-style:
normal; font-variant-caps: normal;
font-weight: normal; text-align: start;
text-indent: 0px;" class="">--
ORCID 0000-0002-1185-3549</div>
<div style="caret-color: rgb(0, 0, 0);
letter-spacing: normal; text-transform:
none; white-space: normal; word-spacing:
0px; text-decoration: none;
-webkit-text-stroke-width: 0px; font-family:
Helvetica; font-size: 12px; font-style:
normal; font-variant-caps: normal;
font-weight: normal; text-align: start;
text-indent: 0px;" class="">-- <a
href="http://www.thyreologie.com.de/"
class="moz-txt-link-freetext"
moz-do-not-send="true">http://www.thyreologie.com.de</a><br
class="">
-- -- -- -- -- -- -- -- -- -- -- -- -- -- --
-- -- -- -- -- -- -- -- -- -- -- -- -- -- --
-- -- -- -- -- —<br class="">
<br class="">
Announcement: Our eBook "Thyroid Hormones
and Cardiac Arrhythmia“ has been published. </div>
<div style="caret-color: rgb(0, 0, 0);
letter-spacing: normal; text-transform:
none; white-space: normal; word-spacing:
0px; text-decoration: none;
-webkit-text-stroke-width: 0px; font-family:
Helvetica; font-size: 12px; font-style:
normal; font-variant-caps: normal;
font-weight: normal; text-align: start;
text-indent: 0px;" class="">You may want
to visit <a
href="http://dx.doi.org/10.3389/978-2-83250-253-2"
class="moz-txt-link-freetext"
moz-do-not-send="true">http://dx.doi.org/10.3389/978-2-83250-253-2</a>
or <a
href="https://www.frontiersin.org/research-topics/16898/thyroid-hormones-and-cardiac-arrhythmia"
class="moz-txt-link-freetext"
moz-do-not-send="true">https://www.frontiersin.org/research-topics/16898/thyroid-hormones-and-cardiac-arrhythmia</a>.<br
class="">
<br class="">
<br class="">
<br class="">
<br class="">
</div>
</div>
</div>
</div>
<br class="">
</div>
<br class="">
<fieldset class="moz-mime-attachment-header"></fieldset>
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