[Biomedical-cybernetics] Two lectures on systems biology in Munich

[Johannes W. Dietrich]

Dear colleagues,

for those of you that are from southern Germany the following two 
lectures by Eberhard Voit that will be held in Munich may be of 
interest.

At 18:25 Uhr +0100 03.07.2008, Christoph Best wrote:
>
>Dear colleagues:
>
>sorry, I got confused in the previous email: Eberhard Voit will be
>giving two seminars in Munich.
>
>The first one on July 7:
>
>     Monday, July 7, 17:00
>
>     Eberhard Voit
>     Georgia Tech and Emory University
>
>     Mathematical Modeling of Combined Genomic and Metabolic Systems
>
>     at the LMU Gene Center in Grosshadern, Lecture Hall, Room 0.75
>
>     Host: P. Cramer. E. Mendoza, 2180 76951
>
>and the second one on July 9 at the bioinformatics colloquium, see below.
>
>
>                           Wednesday, July 9, 18:00
>
>                          Bioinformatics Colloquium
>
>
>                         Systems Biology and its Role in
>
>                   Predictive Health and Personalized Medicine
>
>                                         
>
>                           Prof. Dr. Eberhard O. Voit
>
>                   Director, Integrative BioSystems Institute
>
>                             Atlanta, Georgia U.S.A.
>
>
>                       Room no. B0 52, Theresienstr. 39
>
>                                         
>
>   Recent advances in the natural and computational sciences have made it
>   possible to study health and disease with a new and powerful arsenal of
>   molecular and computational tools. The enormous potential of these tools
>   has focused the spotlight on the possibilities of predicting health
>   processes and personalizing treatment. Bioinformaticians have admirably
>   managed the flood of biomedical data and made methods available for
>   information mining and data driven analysis. However, data and their
>   management alone will be insufficient for a comprehensive understanding
>   of how cells or organisms function and which molecular or physiological
>   changes might lead from health to disease. The reasons for the remaining
>   gap in understanding are manifold but are ultimately associated with the
>   enormous complexity of cells and organisms. A promising approach toward
>   closing the gap in understanding is the construction of integrative
>   mathematical and computational models.  With advances in hardware and
>   software as well as in systems analytical methods, these models are on
>   the brink of becoming sufficiently accurate and comprehensive to yield
>   deep insights into specific disease processes.  While the current models
>   have not yet reached this point, their potential and utility are clearly
>   visible on the horizon.  Under this premise, the presentation will
>   suggest how models can aid our thinking about health and disease beyond
>   the observation that one state is ?normal? and the other is somehow
>   abnormal and therefore diseased.  Specifically, I will define health and
>   disease simplexes, which represent the multi-factorial nature of health
>   and disease and permit the characterization of interpersonal
>   variability, genetic predisposition, life style choices, risk
>   assessments, the investigation of reversible and irreversible
>   trajectories from health to disease and back, and for assessments of
>   alternative treatment strategies. I will formalize these concepts
>   mathematically in the language of Biochemical Systems Theory, which has
>   been used in the past for a variety of analyses of biomedical systems
>   and also provided the first objective rationale for Cox?s proportional
>   hazard model and the linear-logistic disease risk model of epidemiology.
>
>Sorry again for filling your mail boxes.
>-Christoph
>--
>| Christoph Best         <best at ebi.ac.uk>           http://www.ebi.ac.uk/~best
>| European Bioinformatics Institute, Cambridge, UK             +44-1223-492649
>
>Date: Thu, 03 Jul 2008 18:25:23 +0100

Kind regards

J. W. D.

-- 
-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --
-- Dr. Johannes W. Dietrich, M.D.
-- Medizinische Klinik I, Endokrinologie, Diabetologie und Intensivmedizin
-- Berufsgenossenschaftliches Universitaetsklinikum Bergmannsheil
-- Ruhr-Universitaet Bochum
-- Buerkle-de-la-Camp-Platz 1, D-44789 Bochum, NRW, Germany
-- Phone: +49:234:302-6400, Fax: +49:234:302-6403
-- eMail: "j.w.dietrich at medical-cybernetics.de"
-- WWW: http://medical-cybernetics.de
-- WWW: http://www.bergmannsheil.de
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